Jay Bhattacharya dismissed the test-negative design as 'crap.' The biostatistics literature tells a different story.

Medical research is essential for advancing the understanding of health, diseases, and treatments. There are many types of studies that serve different purposes. Medical research, or health research, ...

If CMS cannot persuade GRAIL of the importance of randomization and using cancer death as the outcome, then it should cancel the study. The magnitude of the problem was evident in a major National ...