The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared by the World Health Organization on March 11, 2020. As the number ...

Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...

In the world of gene-expression profiling, microarrays reign, but they are not without drawbacks. Microarrays have trouble with low-abundance transcripts and unidentified genes, for instance.

A large amount of engineering biology studies rely on synthetic DNA, which includes oligonucleotides (oligos) and also longer constructs such as genes or even entire chromosomes 1,2. There is a shift ...

n the mid-1980s, tragedy struck two villages in Leicestershire, England. In two separate instances, three years apart, two teenage girls were raped and murdered on their way home from school. On ...