Northwestern Medicine scientists have discovered new insights into the production and regulation of a class of noncoding RNAs and how alterations in their signatures diversify and modulate the ...

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

Scripps Research postdoctoral researcher Kaushik Chanda explores the mechanisms by which non-coding transcripts modulate neuronal function and structural integrity during learning and memory loss.

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of ...

In a review article, researchers have uncovered compelling evidence that long noncoding RNAs—molecules once dismissed as "junk DNA"—may hold the key to revolutionizing how we diagnose and treat mood ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

“There is strong debate in the scientific community on whether the thousands of long non-coding RNAs generated from our genomes are functional or simply byproducts of a noisy transcriptional machinery ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer cell invasion, tumor microenvironment shaping, ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...