During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

A new study developed a mineralized DNA hydrogel that combines immune regulation with sustained bone regeneration. Using ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now ...

NewLimit Series C raises $435M led by Founders Fund as Armstrong-backed startup moves epigenetic therapies toward human ...

In a recent study posted to the bioRxiv* preprint server, researchers performed age-reversing experiments, in vivo and in vitro, in progeroid mice using gene therapy. Study: Gene Therapy Mediated ...

Researchers have attained the holy grail of cellular reprogramming: inducing pluripotency without using any DNA-based materials. Using only a cocktail of purified proteins and a chemical additive, ...