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alpha_1 Receptors (G_q): Increase IP_3/DAG and intracellular Ca^{2+}, causing vascular smooth muscle contraction (vasoconstriction) and pupillary alpha_2 Receptors (G_i): lDecrease cAMP to inhibit presynaptic norepinephrine release and decrease central sympathetic outflow. beta_1 Receptors (G_s): Increase cAMP in cardiac tissue to increase ...
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